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  4. Recombinant Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D (MGAT4D), partial

Recombinant Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D (MGAT4D), partial

  • 中文名称：
    人MGAT4D重组蛋白
  • 货号：
    CSB-YP405353HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人MGAT4D重组蛋白
  • 货号：
    CSB-EP405353HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人MGAT4D重组蛋白
  • 货号：
    CSB-EP405353HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人MGAT4D重组蛋白
  • 货号：
    CSB-BP405353HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人MGAT4D重组蛋白
  • 货号：
    CSB-MP405353HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    MGAT4D
  • Uniprot No.：
  • 别名：
    MGAT4DAlpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D; N-acetylglucosaminyltransferase MGAT1 inhibitory protein; GlcNAcT-I inhibitory protein; GnT1IP
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    25-374
  • 氨基酸序列
    IYRITQ TNNQLINCRN HILEFKENML HLRNKTEKNT QEMMKVLNRM KYEITKREIL SGNLVAQKAD ILNKNETVSN TFEDLKFFFP HLRKEGRIYP DVIIGKGKTG VSFALGISTV NRGNYSYLKQ TLTSVVSRMT LSQEKDSVVI VLVADSNEDY LHSVVKMITK KFKRQVRSGS LEVISIPAFL YSSMLNAKHL AEASQKLASW RIKQVLDFCI LLLYAQPKAK YYLQLEDDII AKEMYFTKIT DFVGNISSNN WFFIEFSMLG FIGKLFRSED LTHFVRFFLM FYKEKPIDWL LNDIFQVKVC DAGEDLRNCM KRKKQIRIQY KPSLFQHVGI HSSFPRKEQY EKKI
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May play a role in male spermatogenesis. In vitro acts as inhibitor of MGAT1 activity causing cell surface proteins to carry mainly high mannose N-glycans. The function is mediated by its lumenal domain and occurs specifically in the Golgi. A catalytic glucosyltransferase activity is not detected. May be involved in regulation of Sertoli-germ cell interactions during specific stages of spermatogenesis.
  • 基因功能参考文献：
    1. The s show here that the luminal domain of GnT1IP-L contains its MGAT1 inhibitory activity. PMID: 26371870
  • 亚细胞定位：
    Golgi apparatus membrane; Single-pass type II membrane protein. Endoplasmic reticulum membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Glycosyltransferase 54 family
  • 组织特异性：
    Expressed in testis. Poorly expressed in testis biopsies from men with impaired spermatogenesis.
  • 数据库链接：

    HGNC: 43619

    OMIM: 610310

    KEGG: hsa:152586

    STRING: 9606.ENSP00000426225

    UniGene: Hs.189067